Staffed by three Medical Technologists (MT's) and one Medical Laboratory Technician (MLT), who provide 24-hour on-call service, the clinical laboratory aids physicians in diagnosis and treatment.

Most laboratory testing is processed at Coulee Medical Center. Access to a computer network and courier pick-up service, provided by PAML, delivers patient test results within 24-hours, six days a week. Completed test results are then sent to the attending physician for interpretation.

Coulee Medical Center’s Laboratory maintains a high level of competency by participating in proficiency testing programs of the College of American Pathologists and American Association of Bio-analysts. As a result, the lab has high rating scores nationally in "variance of test result" checks.